The mechanisms by which methimazole and/or PTU cause hepatotoxicity are not clarified completely yet, but it seems that these mechanisms might be different between currently available antithyroid drugs.29 Furthermore, the risk factors that render patients more susceptible to antithyroid drugs-induced hepatic injury are not fully recognized
doi:10.1016/S2213-8587(21)00174-1 American Diabetes Association Professional Practice Committee
A: Yes, common routes include oral gavage and subcutaneous injection, and they absolutely impact dosage
10.1016/s0928-4257(99)00119-9 [DOI] [PubMed] [Google Scholar] Sikiric P., Mikus D., Seiwerth S., Grabarevic Z., Rucman R., Petek M., et al
Key steps include: Hydration and fiber adjustments to improve stool form